Track 19: Cerebral Blood Flow and Metabolism
Cerebral blood flow (CBF) is the movement of blood through the network of arteries and veins that supply the brain. In adults, CBF is typically around 750 milliliters per minute, accounting for about 15% of total cardiac output. Arteries deliver oxygenated blood, glucose, and other nutrients to the brain. In neuroimaging techniques like functional magnetic resonance imaging (fMRI) and optical imaging, CBF and the cerebral metabolic rate of oxygen (CMRo(2)) are key drivers of contrast. The relationship between CBF and CMRo(2) during cerebral activation remains a subject of debate, with some experimental findings providing conflicting results. Factors like intracranial pressure and cerebral perfusion pressure, along with the distinctions between anterior and posterior cerebral circulation, further influence brain metabolism and blood flow.
- Anterior Cerebral Circulation
- Posterior Cerebral Circulation
- Role of Intracranial Pressure
- Cerebral Perfusion Pressure
- Neuroimaging